Front Cover: Structure – Bioactivity Relationship in Cyclic Peptoids: An Overview (Eur. J. Org. Chem. 38/2022)

Structure-activity relationship study of novel peptoids that mimic the structure of antimicrobial peptides.

The constant emergence of new bacterial strains that resist the effectiveness of marketed antimicrobials has led to an urgent demand for and intensive research on new classes of compounds to combat bacterial infections. Antimicrobial peptoids comprise one group of potential candidates for antimicrobial drug development. The present study highlights a library of 22 cationic amphipathic peptoids ...

Proceedings Front Cover 8X10

The integrated Rule Oriented Data Management System (iRODS) is a policy-driven data management system that is starting to be used by projects with large data volume requirements that require a highly available system. In this paper we describe an approach to provide a Highly Availability load-balanced iRODS System (HAIRS). We also describe the advantages and disadvantages of the approach and fu...

Outside Front Cover

LUI Front Cover

Pedersen C J. Cyclic polyethers and their complexes with metal salts. J. Amer. Chem. Soc. 89:7017-36. 1967

• The discovery of the first crown ether is described. Forty-seven other aromatic and saturated polyethers were synthesized and their properties determined. Many form stable crystalline complexes with alkali and alkaline earth salts. Some saturated crown ethers solubilize potassium hydroxide and permanganate in aromatic hydrocarbons, EThe SC!5 indicates that this paper has been cited in over 1,...